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GANT61 induces in vitro cell death in ES cell lines. (A) three ES cell... |  Download Scientific Diagram
GANT61 induces in vitro cell death in ES cell lines. (A) three ES cell... | Download Scientific Diagram

Frontiers | GLI1 Inhibitor SRI-38832 Attenuates Chemotherapeutic Resistance  by Downregulating NBS1 Transcription in BRAFV600E Colorectal Cancer
Frontiers | GLI1 Inhibitor SRI-38832 Attenuates Chemotherapeutic Resistance by Downregulating NBS1 Transcription in BRAFV600E Colorectal Cancer

Inhibition of GLI-mediated transcription and tumor cell growth by  small-molecule antagonists | PNAS
Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists | PNAS

Targeting the hedgehog signal transduction pathway at the level of GLI  inhibits neuroblastoma cell growth in vitro and in vivo - Wickström - 2013  - International Journal of Cancer - Wiley Online Library
Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo - Wickström - 2013 - International Journal of Cancer - Wiley Online Library

GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax
GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax

Molecular mechanism of GANT61 combined with doxorubicin in the treatment of  gliomas based on network pharmacology - ScienceDirect
Molecular mechanism of GANT61 combined with doxorubicin in the treatment of gliomas based on network pharmacology - ScienceDirect

GANT-61 induces cell cycle resting and autophagy by down-regulating RNAP  III signal pathway and tRNA-Gly-CCC synthesis to combate chondrosarcoma |  Cell Death & Disease
GANT-61 induces cell cycle resting and autophagy by down-regulating RNAP III signal pathway and tRNA-Gly-CCC synthesis to combate chondrosarcoma | Cell Death & Disease

GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide  treatment | Journal of Experimental & Clinical Cancer Research | Full Text
GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment | Journal of Experimental & Clinical Cancer Research | Full Text

Schematic overview of different GANT61 target sites. Inhibition of the... |  Download Scientific Diagram
Schematic overview of different GANT61 target sites. Inhibition of the... | Download Scientific Diagram

GANT-61 induces cell cycle resting and autophagy by down-regulating RNAP  III signal pathway and tRNA-Gly-CCC synthesis to combate chondrosarcoma |  Cell Death & Disease
GANT-61 induces cell cycle resting and autophagy by down-regulating RNAP III signal pathway and tRNA-Gly-CCC synthesis to combate chondrosarcoma | Cell Death & Disease

GANT61, an inhibitor of Gli1, inhibits the proliferation and migration of  hepatocellular carcinoma cells - Bao-wang Liu, Jing-lin Cao, Yang Wang, Xin  Zhao, Qiang Zeng, Wen-peng Liu, Jun-hong Zhang, Yi-ze Fan, Jian
GANT61, an inhibitor of Gli1, inhibits the proliferation and migration of hepatocellular carcinoma cells - Bao-wang Liu, Jing-lin Cao, Yang Wang, Xin Zhao, Qiang Zeng, Wen-peng Liu, Jun-hong Zhang, Yi-ze Fan, Jian

IJMS | Free Full-Text | GANT61 Reduces Hedgehog Molecule (GLI1) Expression  and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells
IJMS | Free Full-Text | GANT61 Reduces Hedgehog Molecule (GLI1) Expression and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells

GANT61, an inhibitor of Gli1, inhibits the proliferation and migration of  hepatocellular carcinoma cells - Bao-wang Liu, Jing-lin Cao, Yang Wang, Xin  Zhao, Qiang Zeng, Wen-peng Liu, Jun-hong Zhang, Yi-ze Fan, Jian
GANT61, an inhibitor of Gli1, inhibits the proliferation and migration of hepatocellular carcinoma cells - Bao-wang Liu, Jing-lin Cao, Yang Wang, Xin Zhao, Qiang Zeng, Wen-peng Liu, Jun-hong Zhang, Yi-ze Fan, Jian

Full article: Chemical, computational and functional insights into the  chemical stability of the Hedgehog pathway inhibitor GANT61
Full article: Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61

GANT-61 induces cell cycle resting and autophagy by down-regulating RNAP  III signal pathway and tRNA-Gly-CCC synthesis to combate chondrosarcoma |  Cell Death & Disease
GANT-61 induces cell cycle resting and autophagy by down-regulating RNAP III signal pathway and tRNA-Gly-CCC synthesis to combate chondrosarcoma | Cell Death & Disease

Evaluation of Hedgehog Pathway Inhibitors as a Therapeutic Option for  Uterine Leiomyosarcoma Using the Xenograft Model | Reproductive Sciences
Evaluation of Hedgehog Pathway Inhibitors as a Therapeutic Option for Uterine Leiomyosarcoma Using the Xenograft Model | Reproductive Sciences

GANT-61 treatment to RMS cells inhibits proliferation, colony formation...  | Download Scientific Diagram
GANT-61 treatment to RMS cells inhibits proliferation, colony formation... | Download Scientific Diagram

GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax
GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax

GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax
GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax

JCI - Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle  progression and reduces kidney fibrosis
JCI - Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis

Full article: Chemical, computational and functional insights into the  chemical stability of the Hedgehog pathway inhibitor GANT61
Full article: Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61

GANT61 inhibits the transcriptional activity of Gli1 and primary tumor... |  Download Scientific Diagram
GANT61 inhibits the transcriptional activity of Gli1 and primary tumor... | Download Scientific Diagram

A) Exposure to GANT61 (30 µM; 48 hr) reduces expression of both Gli1... |  Download Scientific Diagram
A) Exposure to GANT61 (30 µM; 48 hr) reduces expression of both Gli1... | Download Scientific Diagram

Frontiers | The Combination of Particle Irradiation With the Hedgehog  Inhibitor GANT61 Differently Modulates the Radiosensitivity and Migration  of Cancer Cells Compared to X-Ray Irradiation
Frontiers | The Combination of Particle Irradiation With the Hedgehog Inhibitor GANT61 Differently Modulates the Radiosensitivity and Migration of Cancer Cells Compared to X-Ray Irradiation